Viagra and Pulmonary Arterial Hypertension
Viagra is not only a treatment for erectile dysfunction but an excellent cure against pulmonary arterial hypertension (PAH) or the tightening of blood vessels connected to and within the lungs. This condition often leads to heart failure when not detected and treated earlier. There are many causes of PAH and many more are being studied to further analyze this dreaded disorder. Some people who have rheumatoid arthritis, scleroderma, and systemic lupus erythematosus were reported to have pulmonary arterial hypertension. The causes of PAH can be also be congenital and familial. Patients with family history of PAH are more likely to develop the condition. Symptoms of PAH include dizziness, fainting, and shortness of breath.
The tightening of blood vessels makes it harder for heart, the main organ of the circulatory system, to pump blood. This alteration in the patient's circulatory system leads to massive damages in the body. The organs and the muscles which need nutrients and oxygen are receiving lesser amounts of the valuable substance leading to fibrosis, ischemia, muscle fatigue, dizziness, and accumulation of cellular waste because the bad substances in the cells and tissues are not removed properly. Worse, PAH results to heart attack. Recall that your heart muscle cells are not the same as your skin that easily regenerates. Damages heart cells and tissues are very difficult to restore, and the promising stem-cell research is still at its infancy.
Treatment for PAH includes invasive surgical procedures that aim to remove any clot formation, blockages, and toxins. The latest surgical procedures involve replacing the heart valves and using artificial channels to replace the diseased aorta. Patients are required to change their lifestyles particularly their eating habits. Vasoactive substances like Viagra and Prostaglandins are used to help smooth muscle cells. In the June 14, 2005 issue of the Journal of the American Heart association, a study was published explaining that the sue sildenafil to treat children suffering from PAH, the study noticed that children who used the pill walked faster and breathe easier.
While most people think of Viagra as a cure for erectile dysfunction, many already are using the same drug to cure their pulmonary arterial hypertension. These people buy viagra to stop a possible heart attack. In 2005, the US Federal Drug Administration allowed the marketing of Revatio for PAH. Revatio and Viagra follow the same principle and active substrate known as Sildenafil Citrate. The active ingredient works by stopping a specific enzyme from degrading a substrate necessary for smooth muscle contractions in the pulmonary arteries and the corpus cavernosum of the penis.
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