Inflammatory Bowel Disease-Understand The Etiology
The digestive system is a set of organs that convert the food we eat into nutrients and absorb these nutrients into the bloodstream to fuel our bodies. The term inflammatory bowel disease (IBD) covers a group of disorders in which the intestine become inflamed that is red and swollen, probably as a result of an immune reaction of the body against its own intestinal tissue.
Inflammatory bowel disease is called an idiopathic disease as the cause of the disease is unknown. An unknown agent or factor triggers the body’s immune system to produce an inflammatory reaction in the intestinal tract that continues without control. As a result of the inflammatory reaction, the intestinal wall is damaged leading to bloody diarrhea and abdominal pain. Genetic, infectious, immunologic and psychological factors have all been implicated in influencing the development of inflammatory bowel disease. There is a genetic predisposition to the development of IBD. However, the triggering factor for activation of the body’s immune system has yet to be identified. Factors that can turn on the body’s immune system include an infectious agent, an immune response to an antigen or an autoimmune process. As the intestines are always exposed to things that can cause immune reactions, more recent thinking is that there is a failure of the body to turn off normal immune responses.
There are a range of gastric ulcer medications available in an online pharmacy; however, in cases of inflammatory bowel disease you got to talk to your physician closely to identify the exact problem involved in the condition.
Inflammatory bowel disease refers to two chronic diseases that cause inflammation of the intestines. They are ulcerative colitis and crohn’s disease. Ulcerative colitis is an inflammatory disease of the large intestine, also called the colon. In ulcerative colitis, the inner lining, the mucosa of the intestine becomes inflamed and develops ulcers. Ulcerative colitis is often the most severe in the rectal area, which can cause frequent diarrhea. Mucus and blood often appear in the stool, if the lining of the colon is damaged.
Crohn’s disease differs from ulcerative colitis in the areas of the bowel it involves. It commonly affects the last part of the small intestine which is called the terminal ileum and parts of the large intestine. However, crohn’s disease isn’t limited to these parts and can attack any part of the digestive tract. Crohn’s disease causes inflammation that extends much deeper into the layers of the intestinal wall than ulcerative colitis does. Crohn’s disease generally tends to involve the entire bowel wall, whereas ulcerative colitis affects only the lining of the bowel.
As inflammatory bowel disease is chronic, it will go through periods in which the disease flares up and causes symptoms. These periods are followed by remission, in which symptoms disappear or decrease and good health returns. Symptoms may range from mild to severe and generally depend upon the part of the intestinal tract involved. Loss of appetite, weight loss, fever, bloody diarrhea, abdominal cramps and pain, severe urgency to have bowel movement and anemia due to blood loss are the symptoms of an inflammatory bowel disease. Profuse bleeding from ulcers, acute non-obstructive dilation of the colon, fistulae and perianal disease, colon cancer are considered to be the intestinal complications of inflammatory bowel disease.
Usually a stool examination and a fecal occult blood test are done to eliminate the possibility of bacterial, viral or parasitic causes of diarrhea. Different groups of drugs are used for the treatment of persons with IBD. These include aminosalicylates, corticosteroids, immune modifiers anti-tumor necrosis factor agents and antibiotics.
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