Generic Zantac Produces Marked Inhibition Of Gastric Acid
Generic Zantac falls under the class of hydrogen antagonists which are the first class of highly efficacious drugs for the treatment of acid-peptic disease. It is essentially a hydrogen antihistaminic which inhibits the histamine induced gastric secretion, cardiac stimulation and bronchial relaxation.
Generic Zantac produces marked inhibition of gastric acid by suppressing all the phases of gastric acid secretion in a dose dependent manner. Of all the phases, it blocks basal nocturnal secretion more completely. The pepsin content, volume and intrinsic factor production are all reduced. One good thing about taking Generic Zantac is that it does not affect the absorption of vit B-12 and as such no deficiency of vitamin B-12 occurs.
It is well absorbed orally and the presence of food does not affect it. It has the capacity to cross the placenta and may get secreted in milk. Lactating mothers and pregnant women have to be careful while taking this drug. It is mostly excreted unchanged in urine and bile and has a half life of 2 to 3 hours. If you have any renal problems or renal failure, then you need to have a reduction in the dosage of Generic Zantac.
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