Generic Nexium In Used In The Treatment Of GERD
The normal anatomy of the gastroesophageal system is such that esophagus continues as stomach at an angle which is called the angle of his. There is an anatomical barrier between the lower portion of the esophagus and the upper portion of the stomach. This prevents the back flow of the contents from the stomach to the lower part of the esophagus. This is essential because the pH of the contents of the stomach is much lower than the esophagus and it would hurt the mucosa. In normal people, even if there is a back flow, the contents are cleared off soon. But failure of the lower esophageal sphincter or transient relaxation of the sphincter, impaired clearance of the reflux contents from the esophagus – all these lead to a condition called GERD or gastroesophageal reflux disease.
Generic Nexium is used in the treatment of GERD. You can order the generic versions of these drugs from an online pharmacy instead of their branded versions.
Hiatal hernia is one of the predisposing factors for the development of reflux. Though a little amount of reflux is seen in normal individuals also, yet in people with GERD, the disease is severe and the symptoms are more profound and chronic. In the initial stages of the disease, there are minor changes in the histology of the lower esophagus which may be temporary. But as the disease progresses, there is a gross alteration in the histology of the esophagus leading to a condition called the Barret esophagus. This barret esophagus has the propensity to develop into adenocarcinoma of the colon.
Obesity, scleroderma, and Zollinger Ellison syndrome are also associated with the development of the disease. In people who are too obese, if they suddenly reduce a large amount of fat especially in abdomen, then it might predispose to Hiatal hernia and in turn lead to GERD.
The most common symptom is heart burn which may be at times mistaken for a cardiac symptom. It is accompanied by regurgitation and dysphagia. Other associated symptoms include chest pain, nausea, and pain during swallowing, and excessive salivation, dysphagia or odynophagia
If the reflux extends upwards to the larynx and respiratory tract, then it tends to produce a group of symptoms that are collectively referred to as extra esophageal reflux disease. It includes chronic cough, laryngitis, dental enamel erosion, and asthma.
GERD does not spare children. In children, the symptomatology is quite different and is mostly presented as vomiting up of food, difficulty in feeding, failure to gain weight, bad breath, etc.
If you come across any of these symptoms, wait for sometime till the symptoms disappear. If it disappears, then it is mainly due to some transient issue. But if it persists, it might be a chronic disease that needs accurate diagnosis and proper treatment.
You need to consult a gastroenterologist and would have to go for a diagnostic endoscopy apart from the biopsy that needs to be done of the tissue of the lower esophagus. Treatment includes mainly life style modifications, medicines and surgical management. Lifestyle modifications mainly aim at reducing the conditions that increase the acid secretion like coffee, etc. Medications focus upon reducing the gastric acid secretion.
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other interesting articles submitted by users:
- generic nexium is a very effective drug in treating gastritis
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- generic nexium is prescribed for heart burn
- generic nexium is used in the treatment of symptomatic gastroesophageal reflux
- generic nexium treats heartburn and other symptoms caused by stomach acid
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