Generic Lipitor Is Preferred Over Other Drugs

Statins are the group of best tolerated hypolipidemic drugs that competitively inhibits HMG CO-A reductase- an important enzyme in the synthesis of cholesterol. It was introduced in the 1980s and has been the most efficacious class of drugs since. An important drug that comes in this category is Generic Lipitor. It produces a dose dependent effect and lowers the LDL cholesterol which is termed the bad cholesterol of the body.

The activity of HMG Co-A reductase is the maximum at night; therefore Generic Lipitor is given during bed time. It is effectively orally and is incompletely absorbed from the intestines. From there it reaches the liver and therapeutically reduces cholesterol synthesis by 20 to 50%. Initially there is an increase in cholesterol synthesis by feedback induction which soon reduces by a long term treatment. Finally it is excreted in the bile.

The reason why Generic Lipitor is preferred over other drugs is that it is well tolerated with headache, nausea and bowel upset as the main side effects. Rashes do occur in hypersensitive individuals. Sleep disturbances and muscle tenderness rarely occurs. There are drug interactions and contraindications for the use of this drug for which you would need the advice of your physician.

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