Generic Diflucan Is One Of The Most Extensively Used Antifungal Drugs
Generic Diflucan is one of the most extensively used antifungal drugs for systemic mycosis. It has a greater efficacy, longer half life, fewer side effects and drug interactions. It mainly acts by inhibiting the fungal cytochrome P-450 enzyme that leads to a number of membrane abnormalities in the fungus.
It is a water soluble drug that gets concentrated in vagina, saliva and the nails. In case of renal impairment, the dose has to be reduced. Specific indications for the use of Generic Diflucan are histoplasmosis, fungal meningitis, and candidiasis. It has an oral bioavailability of 94% which does not get affected by the presence of food or gastric ph. This makes it the drug of choice for a number of systemic fungal infections even in the immunocompromised states. The dosage however varies for different infections.
It affects the hepatic metabolism of a number of drugs like phenytoin, cyclosporine, warfarin, etc and increases the plasma levels of these drugs. So you need to be cautious when you use Generic Diflucan along with this drug. You need to know that if you have any infections as aspergillosis, sporotrichosis, and mucormycosis, it is ineffective against these.
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