Generic Bactrim Is A Bioequivalent To The Antibiotic Cotrimoxazole
Generic Bactrim is a bioequivalent to the antibiotic cotrimoxazole. It is essentially a 5:1 combination of the drugs sulfamethoxazole and trimethoprim. Both of them are bacteriostatic drugs and have different mechanism of action. These two drugs achieve a synergism and sometimes become fatal for a number of organisms.
Generic Bactrim is widely used for the treatment of urinary tract infections, respiratory tract infections, typhoid, bacterial diarrheas and dysentery, pneumonia in AIDS and immunocompromised patients, chancroid and is an effective alternative to penicillin for a number of respiratory infections.
It is well absorbed orally and has a half life of 10 hours. It is metabolized in the liver and excreted in urine. If you are taking Generic Bactrim, then the usual manifestations are nausea, vomiting, stomatitis, headache and rashes. Mostly, tolerance develops to all of these. Rarely folate deficiency and blood dyscrasias may occur. Generic Bactrim should not be taken by pregnant women as there is a theoretical teratogenic risk.
People who have renal disorders should have a reduction in their dosage as they tend to develop uremia. Further there is a risk of bone marrow toxicity among the elderly. Diuretics should be avoided as it produces thrombocytopenia when taken with Generic Bactrim.
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